Lifestyle behaviors like working out and improving nutrition can lower the risk of kidney failure in people with chronic kidney disease (CKD), according to new research from the University of Alabama at Birmingham (UAB).

More than 20 million adults in the United States have CKD, and more than 20 percent of adults with hypertension have CKD, according to the Centers for Disease Control and Prevention.

The study published in the Journal of the American Society of Nephrology, led by Paul Muntner, Ph.D, professor in the Department of Epidemiology, examined how following the American Heart Association's "Life's Simple 7," which includes getting active, controllingcholesterol, eating better, managing blood pressure, losing weight, reducing blood sugarand not smoking, affected people with CKD.

"While it is well known that health behaviors and the risk factors we studied are associated with the development of heart disease, the importance of these factors on kidney disease had not been well studied," Muntner explained.

Using data on 3,093 individuals with stage 3 or 4 CKD from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, Muntner and his team evaluated the association between the Life's Simple 7 components and both kidney failure and death.

Over four years, 160 participants developed kidney failure and 610 participants died. Compared with individuals with kidney disease who had zero or one healthy lifestyle components of the Life's Simple 7, those with two, three and four ideal factors had progressively lower risks for kidney failure and death. In participants who followed five to seven of the components, none developed kidney failure.